Synthetic Biology Approaches to Combat Antibiotic Resistant Bacteria

Synthetic biology (SB) is an innovative and emerging field, representing a confluence of science and engineering. It aims to (re)-design biological parts, devices and systems while applying engineering principles for useful applications. Valuable insight gained on the functions of biological systems will further improve the design capacity. The advance of SB is expected to provide solutions to address some of the urgent issues in healthcare, particularly to combat infections caused by multidrug resistant bacteria. Using SB approaches can help to gain new insight into the resistant mechanisms to antibiotics, discover new mechanisms to develop antibiotics, and develop new infectious control strategies. Here, some of these applications of SB in developing novel approaches to combat antibiotic resistant bacteria will be reviewed.